BDBM500539 4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2- pyridyl)-amino]-2,3- dihydropyrrolo [3,4-c]pyridin-1- one::US11021481, Compound I-198::US11021481, Compound I-199::US11078201, Compound I-199::US11548890, Compound I-199

SMILES OC1CCN(CC1)c1ccc(Nc2cnc(c3CNC(=O)c23)-c2cnc3cccnn23)nc1

InChI Key InChIKey=YOQZRAWVXSKRRF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 500539   

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 300nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 550nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 550nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 550nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 550nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500539(4-imidazo[1,2- a]pyridin-3-yl- 7-[(5-morpholino-2-...)
Affinity DataIC50: 550nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent