BDBM50056923 (+)-usnic acid::(9bR)-2,6-diacetyl-3,7,9-trihydroxy-8,9b-dimethyldibenzo[b,d]furan-1(9bH)-one::(R)-usnic acid::CHEMBL367881::d-Usnic acid::d-Usninic acid

SMILES CC(=O)C1C(=O)C=C2Oc3c(c(O)c(C)c(O)c3C(C)=O)[C@@]2(C)C1=O

InChI Key InChIKey=CUCUKLJLRRAKFN-MCEAHNFKSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50056923   

TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibitory concentration of compound against disintegration (reversal of strand transfer)of HIV-1 integraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  1.24E+5nMAssay Description:Inhibitory concentration of compound against strand transfer of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  1.26E+5nMAssay Description:Inhibitory concentration of compound against 3'-processing of HIV-1 integrase in experiment 1&2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged Tdp1 expressed in Escherichia coli BL21 (DE3) using 5'-(5,6 FAM-aac gtc agg gtc ttc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch Of The Russian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured at 1 min interval by fluorimet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4-hydroxyphenylpyruvate dioxygenase(Arabidopsis thaliana)
Universit£

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Arabidopsis thaliana HPPD expressed in Escherichia coli JM105 using HPPA as substrate after preincubated for 15 min followed by substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli)
University Of London

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of Escherichia coli FabI using 2-dodecenoyl-CoA as substrate at pH 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Silla University

Curated by ChEMBL
LigandPNGBDBM50056923((+)-usnic acid | (9bR)-2,6-diacetyl-3,7,9-trihydro...)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed