BDBM50056946 1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butan-1-one::CHEMBL366388

SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12

InChI Key InChIKey=JGHINESLHSSDOZ-UHFFFAOYSA-N

Data  7 KI  1 IC50

Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50056946   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  17nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(CALF)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]prazosin binding to Alpha-1 adrenergic receptor in bovine frontal cortexMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  30nMAssay Description:Inhibition of [3H]DTG binding to sigma receptor in rat hippocampusMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(RAT)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  42nMAssay Description:Inhibition of [3H]pyrilamine binding to Histamine H1 receptor in rat cortexMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(BOVINE)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  110nMAssay Description:Inhibition of [3H]raclopride binding to Dopamine receptor D2 of bovine striatumMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(BOVINE)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of [3H]SCH-23390 binding to Dopamine receptor D1 of bovine striatumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3B(Mus musculus)
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataKi:  3.16E+3nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor in NG cells 108-15More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cooperation Pharmaceutique Fran�aise

Curated by ChEMBL
LigandPNGBDBM50056946(1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-napht...)
Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12
Show InChI InChI=1S/C24H29FN2O/c25-21-12-10-20(11-13-21)24(28)9-4-14-26-15-17-27(18-16-26)23-8-3-6-19-5-1-2-7-22(19)23/h1-2,5,7,10-13,23H,3-4,6,8-9,14-18H2
Affinity DataIC50: 210nMAssay Description:Inhibition of forskolin-activated adenylate cyclase (cAMP) activity at 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair