BDBM50057218 (E)-1-[2-Hydroxy-5-(1H-tetrazol-5-ylmethoxy)-phenyl]-3-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-propenone::1-(5-((1H-tetrazol-5-yl)methoxy)-2-hydroxyphenyl)-3-(3-(2-(quinolin-2-yl)vinyl)phenyl)prop-2-en-1-one::CHEMBL11870

SMILES Oc1ccc(OCc2nnn[nH]2)cc1C(=O)C=Cc1cccc(C=Cc2ccc3ccccc3n2)c1

InChI Key InChIKey=HWJRCRHRKQMNQM-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057218   

TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50057218((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-ylmethoxy)-pheny...)
Affinity DataKd:  45nMAssay Description:Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50057218((E)-1-[2-Hydroxy-5-(1H-tetrazol-5-ylmethoxy)-pheny...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed