BDBM50057950 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-phenyl-1H-imidazole::CHEMBL298296

SMILES CS(=O)(=O)c1ccc(cc1)-n1cc(nc1-c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=ZZBKFGAUXXMYNA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50057950   

TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057950(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50057950(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 240nMAssay Description:Concentration required to inhibit human Prostaglandin G/H synthase 2 (COX-2) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057950(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to inhibit human prostaglandin G/H synthase 1 (COX-1) by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Hyderabad

Curated by ChEMBL
LigandPNGBDBM50057950(2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4...)
Affinity DataIC50: 2.39E+8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed