BDBM50058158 (3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-hexanoylamino)-12-benzyl-9-(3-guanidino-propyl)-15-(3H-imidazol-4-ylmethyl)-6-(1H-indol-3-ylmethyl)-3-methyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,21heptaaza-cyclohexacosane-26-carboxylic acid amide::CHEMBL217584

SMILES CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key InChIKey=WZIILWAZGXRRFZ-OBNAOPLASA-N

Data  6 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50058158   

TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  6.08nMAssay Description:Effective concentration for intracellular cAMP accumulation in L-cells expressing Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  136nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50:  22.4nMAssay Description:Inhibitory concentration against human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50:  141nMAssay Description:Inhibitory concentration against human Melanocortin 5 receptor (hMC5R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  269nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against human Melanocortin 5 receptor (hMC5R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory concentration against human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  2.61nMAssay Description:Effective concentration for intracellular cAMP accumulation in L-cells expressing Melanocortin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataEC50:  6.10nMAssay Description:Effective concentration for intracellular cAMP accumulation in L-cells expressing Melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50:  22nMAssay Description:Inhibitory concentration against human Melanocortin 1 receptor (hMC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50058158((3S,6S,9S,12S,15S,18S,26S)-18-((S)-2-Acetylamino-h...)
Affinity DataIC50:  72nMAssay Description:Inhibitory concentration against human Melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed