BDBM50058554 CHEMBL294028::N-{(2Z)-2-fluoro-3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-enyl}-N-hydroxyurea

SMILES CC(N(O)C(N)=O)C(\F)=C\c1ccc(Oc2ccc(F)cc2)o1

InChI Key InChIKey=BGCFRWIEUHDRBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058554   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058554(N-{(2Z)-2-fluoro-3-[5-(4-fluorophenoxy)-2-furyl]-1...)
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed