BDBM50058554 CHEMBL294028::N-{(2Z)-2-fluoro-3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-enyl}-N-hydroxyurea

SMILES CC(N(O)C(N)=O)C(\F)=C\c1ccc(Oc2ccc(F)cc2)o1

InChI Key InChIKey=BGCFRWIEUHDRBA-JYRVWZFOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058554   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058554(CHEMBL294028 | N-{(2Z)-2-fluoro-3-[5-(4-fluorophen...)
Affinity DataIC50:  90nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed