BDBM50058589 CHEMBL58246::N-[(2E)-3-(2-furyl)-1-methylprop-2-enyl]-N-hydroxyurea

SMILES NC(=O)N(O)C\C=C\c1ccoc1

InChI Key InChIKey=OSVNFJUYRSWWPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058589   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058589(N-[(2E)-3-(2-furyl)-1-methylprop-2-enyl]-N-hydroxy...)
Affinity DataIC50: 440nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058589(N-[(2E)-3-(2-furyl)-1-methylprop-2-enyl]-N-hydroxy...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed