BDBM50058598 CHEMBL58346::N-hydroxy-N-[(2E)-3-thien-3-ylprop-2-enyl]urea

SMILES NC(=O)N(O)C\C=C\c1ccsc1

InChI Key InChIKey=ZBIXBOYBNVVYBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058598   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058598(N-hydroxy-N-[(2E)-3-thien-3-ylprop-2-enyl]urea | C...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 5-lipoxygenase on rat basophil leukemia cell line lysate (RBL-1 2H3 subline) by measuring 5-HETE productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058598(N-hydroxy-N-[(2E)-3-thien-3-ylprop-2-enyl]urea | C...)
Affinity DataIC50: 550nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed