BDBM50058614 CHEMBL62146::N-{3-[5-(4-fluorophenoxy)-2-furyl]-1,1-dimethylprop-2-ynyl}-N-hydroxyurea

SMILES CC(C)(C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O

InChI Key InChIKey=GQFRBPCNLMRESX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058614   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058614(CHEMBL62146 | N-{3-[5-(4-fluorophenoxy)-2-furyl]-1...)
Affinity DataIC50:  150nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed