BDBM50058643 CHEMBL58664::N-{(2E)-3-[5-(4-fluorophenoxy)-2-furyl]-1-methylprop-2-enyl}-N-hydroxyurea::N-{1-[5-(4-fluorophenoxy)furan-2-yl]ethyl}-N-hydroxyurea

SMILES CC(\C=C\c1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O

InChI Key InChIKey=RTJJFGMMZKIEBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058643   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058643(N-{1-[5-(4-fluorophenoxy)furan-2-yl]ethyl}-N-hydro...)
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMed