BDBM50061625 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid::Am 80::CHEMBL25202::Tamibarotene::US11744839, Compound of formula 3::US9963439, AM80::retinobenzoic acid

SMILES CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12

InChI Key InChIKey=MUTNCGKQJGXKEM-UHFFFAOYSA-N

Data  2 KI  6 IC50  3 Kd  3 EC50  1 ITC

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50061625   

TargetRetinoic acid receptor alpha(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetRetinoic acid receptor gamma(Human)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  591nMAssay Description:Agonist activity at RARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Affinity DataEC50:  235nMAssay Description:Agonist activity at RARbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50061625   

CellFlavin reductase (NADPH)(Human)
Korea Basic Science Institute

US Patent
SyringePNGBDBM50061625(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
ITC DataΔG°: -8.00kcal/mole −TΔS°: -3.51kcal/mole ΔH°: -4.49kcal/mole logk: 7.40E+5
T: 25.00°C