BDBM50063315 CHEMBL3398446

SMILES Cc1oc(nc1CCOc1cccc(C[C@@H]2CN(C[C@@H]2C(O)=O)c2nccc(n2)C(F)(F)F)c1)-c1ccccc1

InChI Key InChIKey=CIUUZBXRQNCUIL-GGAORHGYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50063315   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063315(CHEMBL3398446)
Affinity DataIC50:  40nMAssay Description:Binding affinity to PPARgamma (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063315(CHEMBL3398446)
Affinity DataEC50:  14nMAssay Description:Agonist activity at GAL4 tagged human PPARalpha ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063315(CHEMBL3398446)
Affinity DataIC50:  20nMAssay Description:Binding affinity to PPARalpha (unknown origin) using fluorescein-tagged dual PPARalpha/gamma activator by homogeneous fluorescence polarization bindi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development (R & D)

Curated by ChEMBL
LigandPNGBDBM50063315(CHEMBL3398446)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at GAL4 tagged human PPARgamma ligand binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed