BDBM50063787 1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-4-cyclopropyl-butan-1-one::1-(7-tert-butyl-3,3-dimethyl-2,3-dihydrobenzofuran-5-yl)-4-cyclopropylbutan-1-one::CHEMBL13623
SMILES CC(C)(C)c1cc(cc2c1OCC2(C)C)C(=O)CCCC1CC1
InChI Key InChIKey=DAEKZKUAFVMFKP-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50063787
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 1 (COX-1) and is expressed in IC50.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1).More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of 1-lipoxygenase (LOX)in RBL cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:The compound was tested for the concentration (in microM) to inhibit 50% of 5-Lipoxygenase (5-LOX) and is expressed in IC50.More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Concentration (in microM) to inhibit 50% of Prostaglandin G/H synthase 2 (COX-2) and is expressed in IC50.More data for this Ligand-Target Pair