BDBM50068691 CHEMBL149152::Lithium; [6-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4'-isobutyl-biphenyl-2-yloxy]-acetate

SMILES CC(C)Cc1ccc(cc1)-c1c(OCC([O-])=O)cccc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=UUGOVEOBUJMHLD-UHFFFAOYSA-M

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068691   

TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068691(CHEMBL149152 | Lithium; [6-(3,4-dimethyl-isoxazol-...)
Affinity DataKi:  42nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068691(CHEMBL149152 | Lithium; [6-(3,4-dimethyl-isoxazol-...)
Affinity DataKi:  4.00E+3nMAssay Description:Ability to inhibit binding of [125I]-ET-1 to membranes prepared from A10 rat cerebellum (Endothelin B receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed