BDBM50072196 2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-methoxy-quinazolin-7-yloxy]-ethanol::CHEMBL431806

SMILES COc1cc2c(nc(nc2cc1OCCO)-c1cc(OCC2CC2)cc(OCC2CC2)c1)-c1cc(OCC2CC2)cc(OCC2CC2)c1

InChI Key InChIKey=JSKVJOHFPHMSJD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50072196   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072196(2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-m...)
Affinity DataIC50: 7.80E+3nMAssay Description:Evaluated for its ability to inhibit PDE3.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072196(2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-m...)
Affinity DataIC50: 8.50E+3nMAssay Description:Evaluated for its ability to inhibit PDE4D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072196(2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-m...)
Affinity DataIC50: 1.40E+4nMAssay Description:Evaluated for its ability to inhibit PDE4A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50072196(2-[2,4-Bis-(3,5-bis-cyclopropylmethoxy-phenyl)-6-m...)
Affinity DataIC50: 2.20E+4nMAssay Description:Evaluated for its ability to inhibit PDE4B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed