BDBM50075308 (Biphenyl-4-yl-difluoro-methyl)-phosphonic acid::CHEMBL151848::biphenyl-4-yldifluoromethylphosphonic acid

SMILES OP(O)(=O)C(F)(F)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ASGYOLYWKCEISZ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075308   

TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50075308((Biphenyl-4-yl-difluoro-methyl)-phosphonic acid | ...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50075308((Biphenyl-4-yl-difluoro-methyl)-phosphonic acid | ...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075308((Biphenyl-4-yl-difluoro-methyl)-phosphonic acid | ...)
Affinity DataIC50:  7.79E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed