BDBM50075662 3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-enone::CHEMBL23170

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)CC1)c1ccccc1

InChI Key InChIKey=UNHXJQNYRJHGEJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075662   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075662(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...)
Affinity DataIC50:  190nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075662(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...)
Affinity DataIC50:  4.10E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075662(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...)
Affinity DataIC50:  11nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075662(3-(4-Methanesulfonyl-phenyl)-2-phenyl-cyclopent-2-...)
Affinity DataIC50:  3.10E+3nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 in U937 microsomes .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed