BDBM50076254 CHEMBL3416315

SMILES O=S1(=O)C=C(Sc2nnnn2-c2ccccc2)c2ccccc12

InChI Key InChIKey=SZCHWICZALHFML-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50076254   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076254BDBM50076254(CHEMBL3416315)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076254BDBM50076254(CHEMBL3416315)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076254BDBM50076254(CHEMBL3416315)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076254BDBM50076254(CHEMBL3416315)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076254BDBM50076254(CHEMBL3416315)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed