BDBM50076435 CHEMBL3416528

SMILES Cc1ccc(cc1)N1C(=O)CC(Sc2nncn2-c2ccccc2)C1=O

InChI Key InChIKey=XRYMPEYWZQAWLC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50076435   

TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076435BDBM50076435(CHEMBL3416528)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076435BDBM50076435(CHEMBL3416528)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076435BDBM50076435(CHEMBL3416528)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076435BDBM50076435(CHEMBL3416528)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetHistone acetyltransferase GCN5(Baker's yeast)
Mayo Clinic

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50076435BDBM50076435(CHEMBL3416528)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed