BDBM50076593 3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thiol::CHEMBL48969

SMILES SCCCS(=O)(=O)c1ccc(Sc2ccccc2)cc1

InChI Key InChIKey=UGLOKYALFGIDPP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50076593   

TargetStromelysin-1(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50:  150nMAssay Description:Inhibition of matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant matrix metalloproteinase-13 (hMMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant matrix metalloproteinase-1 (hMMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant matrix metalloproteinase-8 (hMMP-8)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50076593(3-(4-Phenylsulfanyl-benzenesulfonyl)-propane-1-thi...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed