BDBM50076667 CHEMBL175995::ethyl 1-methyl-3-[1-(4-methoxyphenyl)-5-(4-methylphenyl)-1H-pyrazol-3-yl]prop-2-ynyl(hydroxy)carbamate

SMILES CCc1ccc(cc1)-c1cc(nn1-c1ccc(OC)cc1)C#CC(C)N(O)C(=O)OC

InChI Key InChIKey=FWGBEXLZWVXAGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076667   

TargetProstaglandin G/H synthase 1/2(RAT)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076667(CHEMBL175995 | ethyl 1-methyl-3-[1-(4-methoxypheny...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against 5-lipoxygenase(5-LO) using broken rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076667(CHEMBL175995 | ethyl 1-methyl-3-[1-(4-methoxypheny...)
Affinity DataIC50:  5.74E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed