BDBM50076789 CHEMBL274672::Lithium; (S)-4-methylsulfanyl-2-({2'-methyl-5-[5-(2-trifluoromethyl-phenyl)-furan-2-ylmethoxymethyl]-biphenyl-2-carbonyl}-amino)-butyrate

SMILES CSCC[C@H](NC(=O)c1ccc(COCc2ccc(o2)-c2ccccc2C(F)(F)F)cc1-c1ccccc1C)C([O-])=O

InChI Key InChIKey=ISLPXYUADRUJGE-UHFFFAOYSA-M

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076789   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50076789(Lithium; (S)-4-methylsulfanyl-2-({2'-methyl-5-[5-(...)Copy SMILESCopy InChI

Affinity DataIC50: 9.90nMAssay Description:In vitro inhibitory activity was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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