BDBM50076806 CHEMBL273265::Lithium; (S)-2-({5-[5-(4-methoxy-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate

SMILES COc1ccc(cc1)-c1ccc(COCc2ccc(C(=O)N[C@@H](CCSC)C([O-])=O)c(c2)-c2ccccc2C)o1

InChI Key InChIKey=FCTWBCRRJCWKTE-LJAQVGFWSA-M

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076806   

LigandPNGBDBM50076806(CHEMBL273265 | Lithium; (S)-2-({5-[5-(4-methoxy-ph...)
Affinity DataIC50:  8.40nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076806(CHEMBL273265 | Lithium; (S)-2-({5-[5-(4-methoxy-ph...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed