BDBM50079356 CHEMBL511201

SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F

InChI Key InChIKey=INYJNSBDHOVLAH-UHFFFAOYSA-N

Data  3 IC50  1 Kd  1 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50079356   

TargetCell division protein FtsZ(Staphylococcus aureus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Staphylococcus aureus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Bacillus subtilis)
Csic

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataKd: <100nMAssay Description:Displacement of free fluorescent probe from inter domain cleft of stabilized Bacillus subtilis FtsZ assessed as dissociation constant in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
TargetCell division protein FtsZ(Staphylococcus aureus)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50079356(CHEMBL511201)
Affinity DataIC50:  154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair