BDBM50079896 CHEMBL3415210

SMILES CCn1c(CNc2ccc(cc2F)C(N)=N)nc2cc(ccc12)C(=O)N(CCC(O)=O)c1cccc(OC)c1

InChI Key InChIKey=VAVOSXMRECUDQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079896   

TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079896(CHEMBL3415210)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of human thrombin using Ac-FVR-AMC as substrate incubated for 10 mins prior to substrate addition measured for 10 min by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079896(CHEMBL3415210)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of thrombin in human blood using fluorogenic Ac-FVR-AMC as substrate by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProthrombin(Homo sapiens (Human))
Shanghai Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50079896(CHEMBL3415210)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed