BDBM50081705 3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol::CHEMBL336126::US20240051978, Compound (I-34)

SMILES CN1CCC(C1)c1c[nH]c2cccc(O)c12

InChI Key InChIKey=DZKMCQNELDTDGP-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081705   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081705(3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol | CHEMB...)
Affinity DataKi:  440nMAssay Description:Compound was tested for binding affinity using [3H]-MDL-100,907 at 5-hydroxytryptamine 2A receptor sites in rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081705(3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol | CHEMB...)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human 5-HT2A receptor assessed as activation of calcium mobilization incubated for 2 mins by Calcium-6 dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081705(3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol | CHEMB...)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human 5-HT2A receptor assessed as activation of calcium mobilization incubated for 2 mins by Calcium-6 dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081705(3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol | CHEMB...)
Affinity DataIC50: <1.00E+3nMAssay Description:Adjust pH to 7.4 followed by 0.2 μM sterile filtration ii. 8 doses of reference and exemplary test compounds were prepared starting from 10 mM s...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50081705(3-(1-Methyl-pyrrolidin-3-yl)-1H-indol-4-ol | CHEMB...)
Affinity DataIC50:  5.50E+3nMAssay Description:Adjust pH to 7.4 followed by 0.2 μM sterile filtration ii. 8 doses of reference and exemplary test compounds were prepared starting from 10 mM s...More data for this Ligand-Target Pair
In DepthDetails US Patent