BDBM50082137 CHEMBL3422660

SMILES NCC(=O)Nc1ccc(Oc2ccc3[nH]cc(C#N)c3c2)cc1

InChI Key InChIKey=FTYQKBVNGALNLT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082137   

Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082137(CHEMBL3422660)
Affinity DataIC50:  6.32E+4nMAssay Description:Inhibition of recombinant human PFKFB2 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082137(CHEMBL3422660)
Affinity DataIC50:  3.76E+4nMAssay Description:Inhibition of recombinant human PFKFB1 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082137(CHEMBL3422660)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of recombinant human PFKFB3 using fructose 6 phosphate as substrate assessed as ADP generation after 1 hr by ADP Glo assayMore data for this Ligand-Target Pair