BDBM50084283 (S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino)-butyric acid::3-Methyl-2-(4'-methyl-biphenyl-4-sulfonylamino)-butyric acid::CHEMBL43113

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccc(C)cc1)C(O)=O

InChI Key InChIKey=MZIZOOUSSMSGAV-KRWDZBQOSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50084283   

TargetCollagenase 3(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  4.50E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  3.89E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50084283((S)-3-methyl-2-(4'-methyl-biphenyl-4-sulfonylamino...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed