BDBM50084761 4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL123563

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(=O)(=O)c1c(C)noc1C

InChI Key InChIKey=XVZWTHXPJUVJAU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084761   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity towards matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  54nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084761(4-(3,5-Dimethyl-isoxazole-4-sulfonyl)-1-(4-methoxy...)
Affinity DataIC50:  1.02E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed