BDBM50085392 Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-carbamimidoyl-2-hydroxy-phenyl)-propyl]-amide}::CHEMBL70328

SMILES NC(=N)c1ccc(O)c(CCCNC(=O)c2ccc(cc2)-c2cccc(c2)C(N)=O)c1

InChI Key InChIKey=LGGSWURRUMPZNN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50085392   

TargetCoagulation factor X(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi:  7nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi: >2.90E+3nMAssay Description:In vitro inhibition of trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi:  3.50E+3nMAssay Description:Compound was tested for its inhibitory activity against PlasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi: >4.00E+3nMAssay Description:In vitro inhibition of coagulation factor IIa.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi: >8.70E+3nMAssay Description:Compound was tested for its inhibitory activity against tissue plasminogen activatorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50085392(Biphenyl-3,4'-dicarboxylic acid 3-amide 4'-{[3-(5-...)
Affinity DataKi:  1.50E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed