BDBM50085501 (1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-one::CHEMBL430840

SMILES Fc1ccc(cc1)[C@H]1C[C@H]2CCC3C1C(=O)CN23

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085501   

TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085501((1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0...)
Affinity DataIC50: 251nMAssay Description:The compound was tested for inhibition of [3H]-5-hydroxy tryptamine uptake in HEK cells by expressing cDNA for human tryptamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085501((1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0...)
Affinity DataIC50: 620nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085501((1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0...)
Affinity DataIC50: 3.32E+3nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed