BDBM50085508 (1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0.0*4,8*]decan-5-ol::CHEMBL101250

SMILES Cc1ccc(cc1)[C@H]1C[C@H]2CCC3C1[C@](C)(O)CN23

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085508   

TargetSodium-dependent serotonin transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085508((1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50: 147nMAssay Description:The compound was tested for inhibition of [3H]-5-hydroxy tryptamine uptake in HEK cells by expressing cDNA for human tryptamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085508((1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50: 296nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085508((1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50: 390nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed