BDBM50086164 CHEMBL275427::N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetamide 0.26(CH3)2CO::N-(4-chlorophenyl)-2-(4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide

SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)Nc2ccc(Cl)cc2)cc1

InChI Key InChIKey=YDLQRGLBZOEJGX-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50086164   

TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  2.47nMAssay Description:Antagonist activity against human A2B adenosine receptor expressed in HEK-293 cells uisng [3H]-ZM-241,385 or [125I]-IABOPXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  6.35nMAssay Description:Antagonist activity against adenosine A1 receptor in rat brain membrane in presence of [3H]-R-PIA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  7.94nMAssay Description:Binding affinity to recombinant human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  49.7nMAssay Description:Antagonist activity against recombinant human adenosine A1 receptor expressed in HEK-293 cells in presence of [125I]-IABA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  50.1nMAssay Description:Binding affinity to recombinant human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  187nMAssay Description:Antagonist activity against recombinant human adenosine A2A receptor expressed in HEK-293 cells in presence of [125I]-iodo-ZM241385 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  191nMAssay Description:Binding affinity to recombinant human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  995nMAssay Description:Antagonist activity against adenosine A2A receptor in rat striatal membrane in presence of [3H]-CGS-21,680 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  1.86E+3nMAssay Description:Binding affinity to recombinant human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50086164(CHEMBL275427 | N-(4-Chloro-phenyl)-2-[4-(2,6-dioxo...)
Affinity DataKi:  1.87E+3nMAssay Description:Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]-IABA radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed