BDBM50086857 5-Methylsulfanyl-2,3-dihydro-benzofuran-7-carboxylic acid ((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL149723

SMILES CSc1cc2CCOc2c(c1)C(=O)NC[C@H]1CCCN1CCc1ccccc1

InChI Key InChIKey=NBJNMUDPZNPIDT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086857   

TargetD(2) dopamine receptor(Human)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086857(5-Methylsulfanyl-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  6.70nMAssay Description:Binding affinity for Dopamine receptor D2 by displacement of [3H]-spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086857(5-Methylsulfanyl-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  100nMAssay Description:Inhibitory concentration against binding of 5-hydroxytryptamine 1A receptor from striata of male Wistar rats by displacement of [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Yoshitomi Pharmaceutical Industries

Curated by ChEMBL
LigandPNGBDBM50086857(5-Methylsulfanyl-2,3-dihydro-benzofuran-7-carboxyl...)
Affinity DataKi:  430nMAssay Description:Binding affinity for 5-hydroxytryptamine 2 receptor from striata of male Wistar rats by displacement of [3H]ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed