BDBM50088388 Benoxaprofen::CHEBI:76114::Compound 90459::Oraflex

SMILES CC(C(O)=O)c1ccc2oc(nc2c1)-c1ccc(Cl)cc1

InChI Key InChIKey=MITFXPHMIHQXPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088388   

TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088388(Benoxaprofen | CHEBI:76114 | Compound 90459 | Oraf...)
Affinity DataIC50:  1.75E+5nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088388(Benoxaprofen | CHEBI:76114 | Compound 90459 | Oraf...)
Affinity DataIC50:  1.04E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088388(Benoxaprofen | CHEBI:76114 | Compound 90459 | Oraf...)
Affinity DataIC50:  9.91E+4nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed