BDBM50090625 3-(3,4-Difluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1-phenyl-1,5-dihydro-pyrrol-2-one::CHEMBL299765

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)N(C1)c1ccccc1)c1ccc(F)c(F)c1

InChI Key InChIKey=YQRPRWFATMATGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50090625   

TargetProstaglandin G/H synthase 2(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090625(3-(3,4-Difluoro-phenyl)-4-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 2 measured as, PGE-2 levels in lipopolysaccharide (LPS)-challenged human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50090625(3-(3,4-Difluoro-phenyl)-4-(4-methanesulfonyl-pheny...)
Affinity DataIC50: 8.20E+3nMAssay Description:Biochemical index for Prostaglandin G/H synthase 1 measured as, thromboxane 2 (TXB2) levels following blood coagulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed