BDBM50091818 CHEMBL61743::Isoquinolin-3-ylamine::uPa_46
SMILES Nc1cc2ccccc2cn1
InChI Key InChIKey=VYCKDIRCVDCQAE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50091818
Affinity DataKi: >3.00E+4nM ΔG°: >-6.17kcal/molepH: 7.4 T: 2°CAssay Description:Abbott uPA__Urokinase Human - Ki(uM)More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+4nMAssay Description:Photometric_Method1More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
Affinity DataIC50: 3.76E+5nMAssay Description:Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...More data for this Ligand-Target Pair