BDBM50092236 CHEMBL71541::{2-[4-(4-Amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-phenoxy]-phenyl}-methanol

SMILES CC(C)n1cc(-c2ccc(Oc3ccccc3CO)cc2)c2c(N)ncnc12

InChI Key InChIKey=QTJNWMQSUXNJOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092236   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092236(CHEMBL71541 | {2-[4-(4-Amino-7-isopropyl-7H-pyrrol...)
Affinity DataIC50:  162nMAssay Description:Inhibitory activity against tie-2 at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092236(CHEMBL71541 | {2-[4-(4-Amino-7-isopropyl-7H-pyrrol...)
Affinity DataIC50: <3nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092236(CHEMBL71541 | {2-[4-(4-Amino-7-isopropyl-7H-pyrrol...)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (VEGFR2) at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed