BDBM50093590 (10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-acetaldehyde oxime::CHEMBL135993

SMILES CC12CCC3C(CCC4=CC(=O)CCC34C)C1CCC2CCN=O

InChI Key InChIKey=UDCMYTPBRSFORA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50093590   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  520nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 human enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  890nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type II expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  1.95E+3nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type I in human DU-145 cell assay at 5 nM of androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of Human steroid 5-alpha-reductase type I expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  300nMAssay Description:Evaluated for the inhibitory activity against human steroid 5-alpha-reductase type 2 from human BPH tissue at 210 nM of testosteroneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of The Saarland

Curated by ChEMBL
LigandPNGBDBM50093590((10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,1...)
Affinity DataIC50:  300nMAssay Description:Evaluated for the inhibitory activity towards Cytochrome P450 17 rat enzyme using testicular microsome at 25 uM of substrate (progesterone)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed