BDBM50093753 (2S,3S)-2-Amino-3-benzyloxy-succinic acid::(2S,3S)-2-amino-3-(benzyloxy)succinic acid::(3S)-3-(BENZYLOXY)-L-ASPARTIC ACID::CHEMBL79140::DL-TBOA
SMILES N[C@@H]([C@H](OCc1ccccc1)C(O)=O)C(O)=O
InChI Key InChIKey=BYOBCYXURWDEDS-IUCAKERBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 32 hits for monomerid = 50093753
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
TargetGlutamate receptor ionotropic, kainate 1(RAT)
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
Suntory Institute For Bioorganic Research
Curated by PDSP Ki Database
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.61E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 6.37E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.61E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.21E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 6.37E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.21E+5nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of [14C]glutamate uptake at human EAAT3 expressed in african green monkey COS1 cellsMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 955nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.29E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)
University Of Groningen
Curated by ChEMBL
University Of Groningen
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 6.40E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute For Bioorganic Research
Curated by ChEMBL
Institute For Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair