BDBM50094505 2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-carbonitrile::2-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-5-carbonitrile::CHEMBL140099

SMILES N#Cc1ccc2[nH]c(CN3CCN(CC3)c3ccccc3)cc2c1

InChI Key InChIKey=TWVIJESEEXGVPP-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50094505   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D4.4 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(short) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity to human D3R assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine receptor D2(long) in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  3.10E+3nMAssay Description:Binding affinity to human D2R assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Laboratoire De Chimie Th�Rapeutique

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]SCH 23990 from dopamine receptor D1 in porcine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(BOVINE)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50094505(2-((4-phenylpiperazin-1-yl)methyl)-1H-indole-5-car...)
Affinity DataKi:  1.30E+4nMAssay Description:Displacement of [3H]SCH-23390 from Dopamine receptor D1 of bovine striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed