BDBM50095136 (3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid 4-[(3-trifluoromethyl-benzoylamino)-methyl]-benzylamide::CHEMBL92880

SMILES CN1CC[C@H]([C@@H](C1)C(=O)NCc1ccc(CNC(=O)c2cccc(c2)C(F)(F)F)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=CYORBGPGFWOAPN-IZZNHLLZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095136   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095136((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi:  35nMAssay Description:Inhibition of [3H]-5-HT uptake into rat synaptosomes by Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095136((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi:  508nMAssay Description:Inhibition of norepinephrine transporter by inhibition of [3H]-NE uptake into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095136((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of [3H]-DA uptake at Dopamine transporter into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed