BDBM50095518 (S)-N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2-methyl-propyl]-2-[2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-acetamidewith 0.7 moles of H20::CHEMBL22927::N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2-methyl-propyl]-2-[2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-acetamide

SMILES CC(C)[C@H](NC(=O)Cn1c(nccc1=O)-c1ccc(F)cc1)C(=O)c1nnc(o1)C(C)(C)C

InChI Key InChIKey=STSRCIMCIOZRSK-SFHVURJKSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095518   

TargetNeutrophil elastase(Homo sapiens (Human))
Cortech

Curated by ChEMBL
LigandPNGBDBM50095518((S)-N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbony...)
Affinity DataKi:  44.3nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Cortech

Curated by ChEMBL
LigandPNGBDBM50095518((S)-N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbony...)
Affinity DataKi:  44.3nMAssay Description:Inhibition of human neutrophil elastase HNE, hydrolysis of MeO-Suc-Ala-Ala-Pro-Val-pNaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed