BDBM50095618 CHEMBL341898::Indatraline::[3-(3,4-Dichloro-phenyl)-indan-1-yl]-methyl-amine;chloride

SMILES CN[C@@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SVFXPTLYMIXFRX-XJKSGUPXSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095618   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  5nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  15nMAssay Description:Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  22nMAssay Description:Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  23nMAssay Description:Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095618(CHEMBL341898 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  27nMAssay Description:Binding affinity against Dopamine transporter using 40-80 pM [125I]RTI.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed