BDBM50098591 CHEMBL3594305

SMILES Nc1nccc2cc(N[C@@H]3c4ccc(CCCC(=O)Nc5cccc(CNC3=O)c5)cc4)ccc12

InChI Key InChIKey=LXFPTSIBSQOGTO-AREMUKBSSA-N

Data  9 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50098591   

TargetKallikrein-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi:  18nMAssay Description:Inhibition of human tissue kallikrein 1 measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 minsMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi:  400nMAssay Description:Inhibition of human Tissue factor/factor 7aMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of human APC measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human trypsin measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of human F10a using S2222 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi: >1.30E+4nMAssay Description:Inhibition of human thrombin using S2238 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor IX(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098591(CHEMBL3594305)
Affinity DataKi: >3.50E+4nMAssay Description:Inhibition of human F9a measured for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed