BDBM50101264 CHEMBL298664::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4-dimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid

SMILES CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1


Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101264   

TargetEndothelin-1 receptor(Homo sapiens (Human))
Novartis Institute for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50101264(CHEMBL298664 | [(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed