BDBM50102470 (4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-yl-acetic acid::CHEMBL79906

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCNCC1)C(O)=O

InChI Key InChIKey=QPSBVVFMTSFAJY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50102470   

TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 30.2nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 264nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 1.76E+3nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 3.89E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102470((4'-Methoxy-biphenyl-4-sulfonylamino)-piperidin-4-...)
Affinity DataIC50: 4.84E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed