BDBM50102481 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanylmethyl-butyric acid::CHEMBL83616

SMILES OC(=O)C(CSc1ccccc1)CC(=O)c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=JXAGDPXECXQWBC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50102481   

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 7.95E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 3.11E+3nMAssay Description:In vitro inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 91.3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 303nMAssay Description:Inhibitory activity against matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50102481(4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-phenylsulfanyl...)
Affinity DataIC50: 1.57E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed