BDBM50103611 CHEBI:31524::DOPS::Droxidopa::L-DOPS

SMILES N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O

InChI Key InChIKey=QXWYKJLNLSIPIN-JGVFFNPUSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103611   

TargetNuclear receptor subfamily 1 group I member 2(Rattus norvegicus)
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50103611(CHEBI:31524 | DOPS | Droxidopa | L-DOPS)
Affinity DataEC50:  6.31E+4nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50103611(CHEBI:31524 | DOPS | Droxidopa | L-DOPS)
Affinity DataEC50:  3.20E+3nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center

Curated by ChEMBL
LigandPNGBDBM50103611(CHEBI:31524 | DOPS | Droxidopa | L-DOPS)
Affinity DataEC50:  4nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed